Medication Therapy

The most prescribed medication for Parkinson’s is Levodopa (Carbidopa/Levodopa).  Levodopa is used to increase dopamine levels in the brain.  Unfortunately, the medication can cause side effects and gradually lose effectiveness over time.   When Levodopa effects diminish many people with Parkinson’s may experience “wearing off” times.  Medications may be adjusted, usually reducing time between doses.

It is extremely important to take PD medications on time and as prescribed by your doctor. This Medication Log, or even a smartphone app, can help keep you on schedule with your medications. Other medications may be used before beginning or in conjunction with Levodopa therapy to increase or extend Levodopa’s effectiveness or minimize side effects.  These drugs include dopamine agonists, COMT inhibitors, MAO-B inhibitors and others.  Dopamine agonists act as dopamine in the brain and the inhibitors aim to stop the body’s natural breakdown of dopamine.  Researchers are investigating PD medications for potential to slow the progression of the disease.

Medical Disclaimer


APDA Medical Mgmt of PD